Basic Information
ID: ALA4324472
Type: Binding
Description: Inverse agonist activity at RORgammat in human whole blood assessed as reduction in Con A/IL-23-stimulated IL-17 secretion after 72 hrs by ELISA
Format: BAO_0000221
Organism: Homo sapiens
Tissue: Blood
Target: Nuclear receptor ROR-gamma(ALA1741186)
Document: ALA4321852
Inverse agonist activity at RORgammat in human whole blood assessed as reduction in Con A/IL-23-stimulated IL-17 secretion after 72 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324472
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 351.86 | 4.31 | 4.31 |
| 370.23 | 4.57 | 4.57 |
| 508.71 | 6.33 | 6.33 |
| 550.79 | 7.52 | 7.52 |
| 514.38 | 6.26 | 6.26 |
| 494.68 | 5.94 | 5.94 |
| 383.28 | 6.34 | 6.34 |
| 349.26 | 5.95 | 5.95 |