Assay Report Card

Basic Information

ID: ALA4324519

Type: Binding

Description: Corrector activity at CFTR F508del mutant (unknown origin) transfected in human HEK293 membrane cells assessed as increase in CFTR level at 3 uM incubated for 24 hrs by using pHTomato probe based fluorescence inverted microscopic analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
430.565.875.87
434.555.775.77
416.535.005.00
422.624.694.69
458.614.894.89
340.472.962.96