Basic Information
ID: ALA4324519
Type: Binding
Description: Corrector activity at CFTR F508del mutant (unknown origin) transfected in human HEK293 membrane cells assessed as increase in CFTR level at 3 uM incubated for 24 hrs by using pHTomato probe based fluorescence inverted microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4321853
Corrector activity at CFTR F508del mutant (unknown origin) transfected in human HEK293 membrane cells assessed as increase in CFTR level at 3 uM incubated for 24 hrs by using pHTomato probe based fluorescence inverted microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324519
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.56 | 5.87 | 5.87 |
| 434.55 | 5.77 | 5.77 |
| 416.53 | 5.00 | 5.00 |
| 422.62 | 4.69 | 4.69 |
| 458.61 | 4.89 | 4.89 |
| 340.47 | 2.96 | 2.96 |