Basic Information
ID: ALA4324538
Type: Binding
Description: Corrector activity at CFTR F508del mutant (unknown origin) transfected in human HEK293 membrane cells assessed as increase in CFTR F508del level at 10 uM incubated for 24 hrs by using pHTomato probe based fluorescence inverted microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Cystic fibrosis transmembrane conductance regulator(ALA4051)
Document: ALA4321853
Corrector activity at CFTR F508del mutant (unknown origin) transfected in human HEK293 membrane cells assessed as increase in CFTR F508del level at 10 uM incubated for 24 hrs by using pHTomato probe based fluorescence inverted microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324538
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.53 | 5.00 | 5.00 |
| 422.62 | 4.69 | 4.69 |
| 458.61 | 4.89 | 4.89 |
| 340.47 | 2.96 | 2.96 |