Assay Report Card

Basic Information

ID: ALA4324543

Type: Binding

Description: Protac activity against VHL/MEK2 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK2 at 0.3 to 3 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1067.97
1062.05
1005.94