Basic Information
ID: ALA4324544
Type: Binding
Description: Protac activity against CRBN/MEK1 in human HT-29 cells harboring BRAF V600E variant assessed as degradation of MEK1 at 0.3 to 3 uM after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4324544
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 808.55 | 3.62 | 3.62 |
| 764.50 | 3.61 | 3.61 |