Assay Report Card

Basic Information

ID: ALA4324562

Type: Binding

Description: Protac activity against VHL/MEK1 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK1 at 3 to 5 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: SK-MEL-28

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1076.08