Assay Report Card

Basic Information

ID: ALA4324568

Type: Binding

Description: Protac activity against VHL/MEK1/2 in human HT-29 cells harboring with BRAF V600E variant assessed as reduction in phosphorylation of MEK at S218/222 residues after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1076.08