Basic Information
ID: ALA4324580
Type: Binding
Description: Protac activity against VHL/MEK1 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK1 by measuring MEK1 protein level up to 1 uM after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4324580
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.20 | 2.47 | 2.47 |
| 1076.08 |