Assay Report Card

Basic Information

ID: ALA4324581

Type: Binding

Description: Protac activity against VHL/MEK2 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring MEK2 protein level up to 1 uM after 24 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
482.202.472.47
1076.08