Basic Information
ID: ALA4324582
Type: Binding
Description: Protac activity against VHL/MEK1 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK1 by measuring MEK1 protein level up to 1 uM after 24 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA4324582
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.20 | 2.47 | 2.47 |
| 1076.08 |