Basic Information
ID: ALA4324591
Type: Binding
Description: Protac activity against VHL/MEK2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK2 by measuring reduction in MEK2 protein level at 0.1 to 0.3 uM after 2 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA4324591
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1076.08 |