Basic Information
ID: ALA4324593
Type: Binding
Description: Protac activity against VHL/MEK1 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as degradation of MEK1 by measuring reduction in MEK1 protein level at 0.3 uM after 4 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA4324593
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1076.08 |