Basic Information
ID: ALA4324601
Type: Binding
Description: Protac activity against VHL/MEK1/2 in human SK-MEL-28 cells harboring with BRAF V600E variant assessed as reduction in phosphorylation of MEK at S218/222 residues at 0.1 to 0.3 after >= 2 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: SK-MEL-28
Activity Charts
Bioactivity
Activity Types for Assay ALA4324601
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1076.08 |