Basic Information
ID: ALA4324608
Type: Binding
Description: Protac activity against VHL/MEK1/2 in human HT-29 cells harboring with BRAF V600E variant assessed as reduction in phosphorylation of ERK at T202/Y204 residues at 0.3 uM after 24 to 144 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA4324608
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1076.08 |