Assay Report Card

Basic Information

ID: ALA4324644

Type: Binding

Description: Protac activity against VHL/cullin9 in human HT-29 cells harboring with BRAF V600E variant assessed as reduction in Cullin9 protein level at 0.1 uM after 10 hrs by LC-MS based Volcano plot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1076.08