Assay Report Card

Basic Information

ID: ALA4324662

Type: Binding

Description: Protac activity against VHL/MEK1 in human HT-29 cells harboring with BRAF V600E variant assessed as degradation of MEK1 at 0.1 to 0.3 uM by Western blot analysis

Organism: Homo sapiens

Cell type: HT-29

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
1076.08