Antagonist activity at CXCR2 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracellu...

Basic Information

ID: ALA4324670

Type: Functional

Description: Antagonist activity at CXCR2 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracellular calcium change incubated for 10 mins by Fluo-4AM dye based fluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target: Interleukin-8 receptor B(ALA2434)

Document: ALA4321855

Antagonist activity at CXCR2 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracellular calcium change incubated for 10 mins by Fluo-4AM dye based fluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4324670

IC50

Total(2)

Parent Molecular Weight	ALogP	Polar Surface Area
395.46	2.57	2.57
392.87	3.76	3.76

Parent Molecular Weight

ALogP

Polar Surface Area

395.46

2.57

392.87

3.76

Antagonist activity at CXCR2 (unknown origin) stably expressed in HEK293 cells co-expressing Galpha16 assessed as reduction in IL-8-induced intracellu...

Basic Information

Activity Charts

Compound Summary