Basic Information
ID: ALA4324681
Type: Functional
Description: Antagonist activity at GFP-tagged CXCR2 (unknown origin) expressed in 293T cells assessed as suppression of IL-8-induced inhibition of forskolin-stimulated cAMP accumulation preincubated for 10 mins followed by IL-8 addition and measured after 10 mins by cAMP assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Interleukin-8 receptor B(ALA2434)
Document: ALA4321855
Antagonist activity at GFP-tagged CXCR2 (unknown origin) expressed in 293T cells assessed as suppression of IL-8-induced inhibition of forskolin-stimulated cAMP accumulation preincubated for 10 mins followed by IL-8 addition and measured after 10 mins by cAMP assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324681
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.54 | 4.65 | 4.65 |