Basic Information
ID: ALA4324682
Type: Binding
Description: Antagonist activity at CXCR2 (unknown origin) expressed in human U2OS cells cp-expressing betaarrestin-2/TEV protease and beta lactamase assessed as effect on beta-arrestin2 recruitment preincubated for 30 mins followed by IL-8 addition and further incubated for 5 hrs subsequently adding CCF4-AM staining and measured after 2 hrs by Tango assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U2OS
Target: Interleukin-8 receptor B(ALA2434)
Document: ALA4321855
Antagonist activity at CXCR2 (unknown origin) expressed in human U2OS cells cp-expressing betaarrestin-2/TEV protease and beta lactamase assessed as effect on beta-arrestin2 recruitment preincubated for 30 mins followed by IL-8 addition and further incubated for 5 hrs subsequently adding CCF4-AM staining and measured after 2 hrs by Tango assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324682
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.55 | 6.20 | 6.20 |
| 464.92 | 6.29 | 6.29 |