Basic Information
ID: ALA4324692
Type: Binding
Description: Selectivity index, ratio of Ki for to displacement of [3H]DAMGO from rat MOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting to Ki for displacement of [3H]U69593 from human KOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA4321856
Selectivity index, ratio of Ki for to displacement of [3H]DAMGO from rat MOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting to Ki for displacement of [3H]U69593 from human KOR expressed in CHO cell membranes incubated for 30 mins by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324692
Ratio Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 529.68 | 3.98 | 3.98 |
| 500.68 | 5.52 | 5.52 |
| 577.73 | 7.21 | 7.21 |
| 540.75 | 6.08 | 6.08 |
| 562.75 | 6.70 | 6.70 |
| 576.74 | 6.34 | 6.34 |
| 514.71 | 5.91 | 5.91 |
| 472.63 | 4.67 | 4.67 |
| 543.75 | 5.06 | 5.06 |
| 595.83 | 5.62 | 5.62 |
| 572.75 | 5.45 | 5.45 |
| 583.77 | 4.76 | 4.76 |
| 590.76 | 6.27 | 6.27 |
| 541.74 | 4.50 | 4.50 |
| 557.78 | 5.45 | 5.45 |
| 514.67 | 5.05 | 5.05 |
| 500.64 | 4.66 | 4.66 |
| 526.72 | 5.69 | 5.69 |
| 695.93 | 5.91 | 5.91 |
| 645.84 | 6.05 | 6.05 |
| 526.72 | 5.91 | 5.91 |
| 486.66 | 5.13 | 5.13 |