Basic Information
ID: ALA4324753
Type: ADME
Description: Transactivation of human PXR receptor expressed in HEPG2 or DPX2 cells co-expressing CYP3A4 promotor by One-Glo luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4324753
MEC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 484.88 | 4.98 | 4.98 |
| 483.94 | 3.54 | 3.54 |
| 431.90 | 3.14 | 3.14 |
| 438.93 | 2.97 | 2.97 |
| 430.91 | 4.27 | 4.27 |
| 456.92 | 3.11 | 3.11 |
| 451.33 | 4.61 | 4.61 |
| 469.32 | 4.75 | 4.75 |
| 451.33 | 4.61 | 4.61 |
| 440.91 | 1.96 | 1.96 |
| 434.88 | 4.10 | 4.10 |
| 430.91 | 4.27 | 4.27 |
| 515.98 | 3.32 | 3.32 |
| 456.92 | 3.11 | 3.11 |
| 446.91 | 3.97 | 3.97 |
| 474.97 | 4.19 | 4.19 |
| 453.31 | 3.40 | 3.40 |
| 410.88 | 2.34 | 2.34 |
| 422.48 | 2.46 | 2.46 |
| 420.88 | 2.69 | 2.69 |
| 500.00 | 5.08 | 5.08 |
| 454.50 | 3.26 | 3.26 |
| 416.89 | 3.96 | 3.96 |
| 430.91 | 4.52 | 4.52 |
| 430.91 | 3.75 | 3.75 |
| 530.00 | 3.43 | 3.43 |
| 451.33 | 4.61 | 4.61 |
| 434.88 | 4.10 | 4.10 |
| 477.37 | 5.10 | 5.10 |
| 456.92 | 3.11 | 3.11 |
| 472.49 | 3.34 | 3.34 |
| 485.78 | 5.27 | 5.27 |
| 416.89 | 3.96 | 3.96 |
| 430.91 | 4.27 | 4.27 |
| 417.87 | 3.36 | 3.36 |
| 452.32 | 4.01 | 4.01 |
| 474.97 | 4.19 | 4.19 |
| 422.93 | 3.88 | 3.88 |
| 417.87 | 3.36 | 3.36 |
| 456.92 | 3.11 | 3.11 |
| 416.89 | 3.96 | 3.96 |
| 486.98 | 4.46 | 4.46 |
| 444.94 | 3.79 | 3.79 |
| 515.98 | 3.32 | 3.32 |
| 484.88 | 4.98 | 4.98 |
| 474.97 | 4.19 | 4.19 |
| 446.91 | 3.97 | 3.97 |
| 473.94 | 3.92 | 3.92 |
| 408.91 | 3.35 | 3.35 |
| 465.36 | 5.18 | 5.18 |