Basic Information
ID: ALA4324933
Type: Functional
Description: Antagonist activity at mouse mu opioid receptor expressed in CHO cells cotransfected with Galphaqi5 assessed as inhibition of DAMGO-induced increase in intracellular calcium concentration preincubated for 60 mins in Fluo4AM solution followed by compound addition and further incubated for 15 mins followed by DAMGO stimulation by Fluo4AM dye based assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: CHO
Target: Mu opioid receptor(ALA2858)
Document: ALA4321862
Antagonist activity at mouse mu opioid receptor expressed in CHO cells cotransfected with Galphaqi5 assessed as inhibition of DAMGO-induced increase in intracellular calcium concentration preincubated for 60 mins in Fluo4AM solution followed by compound addition and further incubated for 15 mins followed by DAMGO stimulation by Fluo4AM dye based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4324933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 327.38 | 1.30 | 1.30 |
| 523.03 | 3.50 | 3.50 |
| 523.03 | 3.50 | 3.50 |
| 539.10 | 3.97 | 3.97 |