Basic Information
ID: ALA4324962
Type: Binding
Description: Binding affinity to recombinant Pseudomonas aeruginosa LpxC C40S mutant (1 to 299 residues) expressed in Escherichia coli BL21 AI cells assessed as change in melting temperature at 25 uM SYPRO orange dye based differential scanning fluorimetric method
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA4324962
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 412.44 | 1.36 | 1.36 |
| 439.47 | 1.79 | 1.79 |
| 451.48 | 1.55 | 1.55 |
| 525.63 | 1.57 | 1.57 |
| 433.49 | -0.05 | -0.05 |
| 433.49 | -0.05 | -0.05 |
| 473.55 | 1.60 | 1.60 |
| 435.46 | -0.91 | -0.91 |
| 402.40 | 0.95 | 0.95 |
| 450.54 | 0.39 | 0.39 |
| 433.49 | 0.10 | 0.10 |
| 421.48 | 0.10 | 0.10 |
| 492.58 | 0.83 | 0.83 |
| 522.61 | 0.42 | 0.42 |
| 470.53 | -1.13 | -1.13 |
| 438.53 | 0.53 | 0.53 |
| 485.56 | 1.47 | 1.47 |
| 507.01 | 1.32 | 1.32 |
| 485.56 | 1.47 | 1.47 |
| 452.51 | -0.48 | -0.48 |
| 462.53 | -0.34 | -0.34 |
| 485.56 | 1.39 | 1.39 |
| 432.50 | 0.47 | 0.47 |
| 454.94 | -0.18 | -0.18 |
| 440.45 | 1.18 | 1.18 |
| 402.40 | 0.95 | 0.95 |
| 423.45 | -1.32 | -1.32 |
| 452.46 | 2.11 | 2.11 |
| 456.52 | 2.22 | 2.22 |
| 450.54 | 0.39 | 0.39 |
| 475.52 | 0.40 | 0.40 |
| 504.59 | 1.02 | 1.02 |
| 520.56 | -0.08 | -0.08 |
| 450.49 | 2.16 | 2.16 |
| 484.57 | 1.97 | 1.97 |
| 446.48 | -0.54 | -0.54 |
| 450.54 | 0.53 | 0.53 |
| 531.66 | 1.63 | 1.63 |
| 572.64 | 1.46 | 1.46 |
| 490.60 | 2.03 | 2.03 |
| 514.60 | 1.20 | 1.20 |
| 487.53 | 0.59 | 0.59 |
| 471.99 | 0.25 | 0.25 |