Basic Information
ID: ALA4324993
Type: Binding
Description: Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as induction of AR degradation at 1 uM incubated for 6 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: LNCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA4324993
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1022.69 | ||
| 946.59 | 7.44 | 7.44 |
| 994.43 | 8.12 | 8.12 |
| 1012.67 | ||
| 939.55 | 7.34 | 7.34 |
| 998.67 | 7.82 | 7.82 |
| 970.61 | 7.04 | 7.04 |
| 970.61 | 7.04 | 7.04 |
| 1033.11 | ||
| 933.52 | 7.50 | 7.50 |
| 892.50 | 6.42 | 6.42 |
| 891.51 | 7.48 | 7.48 |
| 1077.56 | ||
| 915.53 | 7.36 | 7.36 |
| 1095.81 | ||
| 949.98 | 8.01 | 8.01 |
| 891.51 | 5.78 | 5.78 |
| 946.59 | 7.16 | 7.16 |
| 1023.68 | ||
| 940.54 | 7.23 | 7.23 |
| 974.64 | 6.25 | 6.25 |
| 1016.66 |