Basic Information
ID: ALA4325003
Type: Binding
Description: Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as AR degradation at 100 nM preincubated with NEDD8-activating E1 enzyme inhibitor, MLN4924 for 2 hrs followed by incubation with compound for 6 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: LNCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA4325003
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 915.53 | 7.36 | 7.36 |