Assay Report Card

Basic Information

ID: ALA4325004

Type: Binding

Description: Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as AR degradation at 100 nM preincubated with proteasome inhibitor, MG132 for 2 hrs followed by incubation with compound for 6 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: LNCaP

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
915.537.367.36