Potency index, ratio of IC50 for AR antagonist N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-...

ID: ALA4325016

Type: Functional

Description: Potency index, ratio of IC50 for AR antagonist N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxamide to IC50 for test compound against AR-positive human VCaP cells incubated for 7 days in presence of AR agonist R1881 by WST-8 assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: VCaP

Target:  VCaP(ALA4296508)

Document:  ALA4321866

Potency index, ratio of IC50 for AR antagonist N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxamide to IC50 for test compound against AR-positive human VCaP cells incubated for 7 days in presence of AR agonist R1881 by WST-8 assay: 1