Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as reduction in FKBP5 mRNA expression level incubated for 24 hrs by qRT-PCR a...

Basic Information

ID: ALA4325020

Type: Binding

Description: Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as reduction in FKBP5 mRNA expression level incubated for 24 hrs by qRT-PCR analysis relative to N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxamide

Format: BAO_0000219

Organism: Homo sapiens

Cell type: LNCaP

Target:  VHL/Androgen receptor(ALA4523730)

Document:  ALA4321866

Protac activity against VHL/AR in AR-positive human LNCAP cells assessed as reduction in FKBP5 mRNA expression level incubated for 24 hrs by qRT-PCR analysis relative to N-((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-hydroxyethyl)-1H-pyrazole-4-carboxamide: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
915.537.367.36