Basic Information
ID: ALA4325027
Type: Binding
Description: Inhibition of recombinant Escherichia coli LpxC (1 to 300 residues) C125S mutant expressed in Escherichia coli BL21 AI assessed as change in melting temperature at 25 uM by Sypro orange dye based differential scanning fluorimetry
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4325027
deltaTm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.53 | -0.75 | -0.75 |
| 432.50 | 0.08 | 0.08 |
| 446.53 | 0.28 | 0.28 |
| 460.56 | 0.67 | 0.67 |
| 464.52 | 0.23 | 0.23 |
| 436.47 | -0.36 | -0.36 |
| 418.48 | -0.46 | -0.46 |
| 476.56 | -0.22 | -0.22 |
| 432.50 | 0.06 | 0.06 |
| 478.55 | 0.76 | 0.76 |
| 432.50 | -0.11 | -0.11 |
| 482.51 | 0.52 | 0.52 |
| 450.49 | -0.02 | -0.02 |
| 490.58 | 0.03 | 0.03 |
| 474.54 | -0.34 | -0.34 |
| 416.50 | -0.13 | -0.13 |
| 502.59 | 0.44 | 0.44 |
| 418.48 | -0.18 | -0.18 |
| 446.53 | 0.42 | 0.42 |
| 460.51 | -0.20 | -0.20 |
| 460.56 | 0.67 | 0.67 |