Basic Information
ID: ALA4325028
Type: Binding
Description: Inhibition of recombinant Pseudomonas aeruginosa LpxC (1 to 299 residues) C40S mutant expressed in Escherichia coli BL21 AI assessed as change in melting temperature at 25 uM by Sypro orange dye based differential scanning fluorimetry
Organism: Pseudomonas aeruginosa
Activity Charts
Bioactivity
Activity Types for Assay ALA4325028
deltaTm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.53 | -0.75 | -0.75 |
| 432.50 | 0.08 | 0.08 |
| 446.53 | 0.28 | 0.28 |
| 460.56 | 0.67 | 0.67 |
| 464.52 | 0.23 | 0.23 |
| 436.47 | -0.36 | -0.36 |
| 418.48 | -0.46 | -0.46 |
| 476.56 | -0.22 | -0.22 |
| 432.50 | 0.06 | 0.06 |
| 478.55 | 0.76 | 0.76 |
| 432.50 | -0.11 | -0.11 |
| 482.51 | 0.52 | 0.52 |
| 450.49 | -0.02 | -0.02 |
| 490.58 | 0.03 | 0.03 |
| 474.54 | -0.34 | -0.34 |
| 416.50 | -0.13 | -0.13 |
| 502.59 | 0.44 | 0.44 |
| 418.48 | -0.18 | -0.18 |
| 446.53 | 0.42 | 0.42 |
| 460.51 | -0.20 | -0.20 |
| 460.56 | 0.67 | 0.67 |