Basic Information
ID: ALA4325036
Type: Functional
Description: In vivo antibacterial activity against Escherichia coli ATCC 25922 A-935 infected in NMRI or ICR CD1 mouse neutropenic thigh infection model assessed as change in log10CFU at 150 mg/kg, sc administered 2 hrs post infection and measured per thigh after 24 hrs by serial dilution method
Organism: Escherichia coli
Strain: ATCC 25922 A-935
Activity Charts
Bioactivity
Activity Types for Assay ALA4325036
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.48 | 0.05 | 0.05 |
| 462.53 | -0.75 | -0.75 |
| 433.49 | -0.05 | -0.05 |
| 433.49 | 0.10 | 0.10 |
| 463.51 | -0.69 | -0.69 |
| 464.52 | 0.23 | 0.23 |
| 432.50 | -0.11 | -0.11 |
| 490.58 | 0.03 | 0.03 |
| 418.48 | -0.18 | -0.18 |