Basic Information
ID: ALA4325121
Type: Binding
Description: Agonist activity at STING in human THP1 cells assessed as stimulation of IRF3 pathway measured after 20 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4325121
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.56 | 3.23 | 3.23 |
| 403.44 | 3.35 | 3.35 |
| 646.75 | 3.33 | 3.33 |
| 533.59 | 3.24 | 3.24 |
| 353.38 | 2.20 | 2.20 |
| 485.55 | 2.91 | 2.91 |
| 482.54 | 3.10 | 3.10 |
| 529.60 | 4.03 | 4.03 |
| 399.45 | 3.02 | 3.02 |
| 505.54 | 2.45 | 2.45 |
| 616.68 | 2.60 | 2.60 |
| 513.56 | 1.38 | 1.38 |
| 499.57 | 2.84 | 2.84 |
| 552.59 | 4.26 | 4.26 |
| 341.42 | 3.23 | 3.23 |
| 505.54 | 2.45 | 2.45 |
| 674.42 | -2.34 | -2.34 |
| 370.41 | 2.02 | 2.02 |
| 503.56 | 2.74 | 2.74 |
| 504.55 | 3.05 | 3.05 |
| 502.53 | 3.11 | 3.11 |
| 548.60 | 3.93 | 3.93 |
| 380.45 | 3.13 | 3.13 |
| 561.60 | 2.91 | 2.91 |
| 621.70 | 3.09 | 3.09 |
| 403.44 | 3.35 | 3.35 |
| 560.61 | 3.51 | 3.51 |
| 499.53 | 1.29 | 1.29 |
| 503.52 | 2.50 | 2.50 |
| 356.39 | 1.54 | 1.54 |
| 354.37 | 1.60 | 1.60 |
| 354.41 | 2.32 | 2.32 |
| 483.53 | 2.49 | 2.49 |
| 554.61 | 4.20 | 4.20 |
| 405.46 | 3.30 | 3.30 |
| 490.56 | 4.14 | 4.14 |
| 532.61 | 2.46 | 2.46 |
| 552.59 | 4.26 | 4.26 |
| 522.61 | 2.74 | 2.74 |
| 356.39 | 1.54 | 1.54 |
| 470.53 | 2.22 | 2.22 |
| 399.46 | 1.27 | 1.27 |
| 471.52 | 2.82 | 2.82 |
| 519.56 | 2.93 | 2.93 |
| 508.58 | 2.49 | 2.49 |
| 483.57 | 2.47 | 2.47 |
| 615.69 | 3.20 | 3.20 |