Assay Report Card

Basic Information

ID: ALA4325325

Type: Binding

Description: Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system using MCM2 as substrate preincubated with enzyme for 10 mins prior to 1 uM ATP addition by HTRF transcreener ADP assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4325325

IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
315.40	2.28	2.28
341.44	2.84	2.84
386.31	1.89	1.89
388.32	2.50	2.50
374.30	2.11	2.11
287.35	1.72	1.72
388.32	2.35	2.35
363.87	2.42	2.42
329.43	2.89	2.89
388.32	2.28	2.28
386.31	2.27	2.27
329.43	2.89	2.89
388.32	2.35	2.35
405.83	3.21	3.21
341.44	2.84	2.84
388.32	2.50	2.50
388.32	2.45	2.45