Assay Report Card

Basic Information

ID: ALA4325326

Type: Binding

Description: Inhibition of N-terminal GST-tagged full-length human CDK2 (1 to 298 residues)/Cyclin E (1 to 410 residues) expressed in baculovirus expression system using histone H1 as susbtrate after 90 mins by Kinase-Glo luminescence assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4325326

IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
315.40	2.28	2.28
341.44	2.84	2.84
386.31	1.89	1.89
388.32	2.50	2.50
374.30	2.11	2.11
287.35	1.72	1.72
388.32	2.35	2.35
363.87	2.42	2.42
329.43	2.89	2.89
388.32	2.28	2.28
386.31	2.27	2.27
329.43	2.89	2.89
388.32	2.35	2.35
405.83	3.21	3.21
341.44	2.84	2.84
388.32	2.50	2.50
388.32	2.45	2.45