Assay Report Card

Basic Information

ID: ALA4325328

Type: Binding

Description: Selectivity index, ratio of IC50 for N-terminal GST-tagged full-length human CDK2 (1 to 298 residues)/Cyclin E (1 to 410 residues) expressed in baculovirus expression system to IC50 for N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4325328

Ratio IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
315.40	2.28	2.28
341.44	2.84	2.84
386.31	1.89	1.89
388.32	2.50	2.50
374.30	2.11	2.11
287.35	1.72	1.72
388.32	2.35	2.35
363.87	2.42	2.42
329.43	2.89	2.89
388.32	2.28	2.28
386.31	2.27	2.27
329.43	2.89	2.89
388.32	2.35	2.35
405.83	3.21	3.21
341.44	2.84	2.84
388.32	2.50	2.50
388.32	2.45	2.45