Assay Report Card

Basic Information

ID: ALA4325329

Type: Binding

Description: Selectivity index, ratio of IC50 N-terminal GST-tagged human ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system to IC50 for N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA4325329

Ratio IC50

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
315.40	2.28	2.28
341.44	2.84	2.84
386.31	1.89	1.89
388.32	2.50	2.50
374.30	2.11	2.11
287.35	1.72	1.72
388.32	2.35	2.35
363.87	2.42	2.42
329.43	2.89	2.89
388.32	2.28	2.28
386.31	2.27	2.27
329.43	2.89	2.89
388.32	2.35	2.35
405.83	3.21	3.21
341.44	2.84	2.84
388.32	2.50	2.50
388.32	2.45	2.45