Assay Report Card

Basic Information

ID: ALA4325331

Type: Binding

Description: Inhibition of N-terminal GST-fused full-length human CDC7 (1 to 574 end residues)/DBF4 (1 to 674 residues) expressed in baculovirus expression system using MCM2 as substrate preincubated with enzyme for 60 mins prior to 50 uM ATP addition by HTRF transcreener ADP assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
315.402.282.28
341.442.842.84
386.311.891.89
388.322.502.50
405.833.213.21