Basic Information
ID: ALA4325398
Type: Functional
Description: Antagonist activity at human EP2 transfected in rat C6 cells assessed as decrease in intracellular cAMP incubated for 10 mins followed by PGE2 addition and measured after 40 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: C6
Target: Prostanoid EP2 receptor(ALA1881)
Document: ALA4321875
Antagonist activity at human EP2 transfected in rat C6 cells assessed as decrease in intracellular cAMP incubated for 10 mins followed by PGE2 addition and measured after 40 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4325398
Kb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.47 | 3.81 | 3.81 |
| 363.46 | 3.29 | 3.29 |
| 355.44 | 4.51 | 4.51 |
| 386.46 | 3.69 | 3.69 |
| 384.48 | 5.12 | 5.12 |
| 386.46 | 3.91 | 3.91 |
| 412.49 | 4.47 | 4.47 |
| 373.43 | 4.65 | 4.65 |
| 372.43 | 3.38 | 3.38 |
| 415.49 | 4.53 | 4.53 |
| 385.47 | 4.52 | 4.52 |
| 364.45 | 2.68 | 2.68 |
| 388.43 | 3.08 | 3.08 |
| 371.44 | 4.22 | 4.22 |
| 372.43 | 3.38 | 3.38 |
| 397.44 | 3.25 | 3.25 |
| 436.95 | 3.99 | 3.99 |
| 390.42 | 3.52 | 3.52 |
| 414.47 | 3.58 | 3.58 |
| 412.49 | 4.47 | 4.47 |
| 372.43 | 3.38 | 3.38 |
| 414.47 | 3.58 | 3.58 |
| 401.47 | 3.16 | 3.16 |
| 430.51 | 4.00 | 4.00 |
| 390.42 | 3.52 | 3.52 |
| 362.48 | 3.83 | 3.83 |
| 414.47 | 3.58 | 3.58 |
| 428.54 | 4.67 | 4.67 |
| 416.49 | 3.49 | 3.49 |
| 454.46 | 4.70 | 4.70 |
| 385.47 | 4.52 | 4.52 |
| 402.47 | 5.26 | 5.26 |
| 386.46 | 3.69 | 3.69 |
| 418.48 | 4.13 | 4.13 |
| 385.47 | 4.52 | 4.52 |
| 344.42 | 3.77 | 3.77 |
| 436.47 | 4.27 | 4.27 |
| 400.49 | 3.99 | 3.99 |
| 400.49 | 3.99 | 3.99 |
| 415.49 | 4.53 | 4.53 |
| 428.54 | 4.67 | 4.67 |
| 414.47 | 3.63 | 3.63 |
| 402.46 | 3.39 | 3.39 |
| 434.93 | 4.65 | 4.65 |
| 469.38 | 5.30 | 5.30 |
| 444.54 | 3.99 | 3.99 |