Basic Information
ID: ALA4325429
Type: ADME
Description: Intrinsic clearance in human liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4325429
CLH
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 536.48 | 3.68 | 3.68 |
| 462.51 | 2.53 | 2.53 |
| 549.48 | 2.62 | 2.62 |
| 558.49 | 2.67 | 2.67 |
| 462.51 | 2.53 | 2.53 |
| 530.50 | 3.46 | 3.46 |
| 521.55 | 2.47 | 2.47 |
| 558.49 | 3.70 | 3.70 |
| 494.52 | 3.06 | 3.06 |
| 558.49 | 2.67 | 2.67 |
| 548.49 | 3.60 | 3.60 |
| 530.50 | 3.46 | 3.46 |
| 550.47 | 3.05 | 3.05 |
| 476.53 | 2.92 | 2.92 |
| 504.59 | 3.70 | 3.70 |
| 530.56 | 3.55 | 3.55 |
| 520.56 | 3.45 | 3.45 |
| 530.50 | 3.46 | 3.46 |
| 558.49 | 2.67 | 2.67 |
| 476.53 | 2.92 | 2.92 |
| 476.53 | 2.92 | 2.92 |
| 502.57 | 3.31 | 3.31 |
| 549.48 | 2.62 | 2.62 |
| 529.57 | 3.12 | 3.12 |
| 521.55 | 2.47 | 2.47 |
| 478.51 | 2.37 | 2.37 |
| 557.50 | 3.27 | 3.27 |
| 504.59 | 3.56 | 3.56 |