Assay Report Card

Basic Information

ID: ALA4325431

Type: ADME

Description: Intrinsic clearance in mouse liver microsomes assessed per mg protein at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured up to 60 mins by UPLC-MS/MS analysis

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
536.483.683.68
462.512.532.53
549.482.622.62
558.492.672.67
462.512.532.53
530.503.463.46
521.552.472.47
558.493.703.70
494.523.063.06
558.492.672.67
548.493.603.60
530.503.463.46
550.473.053.05
476.532.922.92
504.593.703.70
530.563.553.55
520.563.453.45
530.503.463.46
558.492.672.67
476.532.922.92
476.532.922.92
502.573.313.31
549.482.622.62
529.573.123.12
521.552.472.47
478.512.372.37
557.503.273.27
504.593.563.56