Basic Information
ID: ALA4325517
Type: Binding
Description: Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured over 20 mins by amplex red reagent-based horseradish peroxidase-coupled fluorometric assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Monoamine oxidase B(ALA2039)
Document: ALA4321878
Inhibition of recombinant human microsomal MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 mins followed by substrate addition and measured over 20 mins by amplex red reagent-based horseradish peroxidase-coupled fluorometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4325517
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 272.18 | 3.33 | 3.33 |
| 159.23 | 1.75 | 1.75 |
| 171.24 | 1.90 | 1.90 |
| 187.29 | 2.18 | 2.18 |
| 281.32 | 3.38 | 3.38 |
| 245.34 | 3.10 | 3.10 |
| 303.43 | 2.45 | 2.45 |
| 277.77 | 3.84 | 3.84 |
| 259.78 | 3.70 | 3.70 |
| 293.33 | 4.06 | 4.06 |
| 245.34 | 3.10 | 3.10 |
| 243.32 | 3.18 | 3.18 |
| 265.40 | 3.92 | 3.92 |
| 243.32 | 3.18 | 3.18 |
| 227.35 | 2.96 | 2.96 |
| 267.42 | 4.17 | 4.17 |
| 243.32 | 3.18 | 3.18 |
| 293.33 | 4.06 | 4.06 |
| 268.36 | 2.14 | 2.14 |
| 293.33 | 4.06 | 4.06 |
| 295.35 | 3.98 | 3.98 |
| 225.34 | 3.05 | 3.05 |
| 243.35 | 2.67 | 2.67 |
| 250.35 | 2.92 | 2.92 |
| 277.77 | 3.84 | 3.84 |
| 270.38 | 2.06 | 2.06 |
| 279.31 | 3.46 | 3.46 |
| 243.32 | 3.18 | 3.18 |
| 303.43 | 2.45 | 2.45 |
| 268.36 | 2.14 | 2.14 |
| 257.38 | 2.97 | 2.97 |
| 245.34 | 3.10 | 3.10 |
| 269.43 | 3.92 | 3.92 |
| 295.35 | 3.98 | 3.98 |
| 252.36 | 2.84 | 2.84 |
| 304.23 | 3.81 | 3.81 |
| 259.78 | 3.70 | 3.70 |
| 241.38 | 3.27 | 3.27 |
| 239.36 | 3.35 | 3.35 |
| 269.43 | 4.09 | 4.09 |
| 281.32 | 3.38 | 3.38 |
| 239.36 | 3.35 | 3.35 |
| 255.36 | 3.05 | 3.05 |
| 265.40 | 3.92 | 3.92 |
| 267.42 | 4.17 | 4.17 |
| 245.34 | 3.10 | 3.10 |
| 243.32 | 3.18 | 3.18 |
| 243.32 | 3.18 | 3.18 |
| 250.35 | 2.92 | 2.92 |
| 261.80 | 3.62 | 3.62 |
| 293.33 | 4.06 | 4.06 |
| 279.31 | 3.46 | 3.46 |