Basic Information
ID: ALA4325800
Type: Binding
Description: Inhibition of human placenta CatD at 50 nM using Abz-Lys-Pro-Ala-Glu-Phe-Nph-Ala-Leu as substrate preincubated for 10 mins followed by substrate addition and measured by FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Cathepsin D(ALA2581)
Document: ALA4321885
Inhibition of human placenta CatD at 50 nM using Abz-Lys-Pro-Ala-Glu-Phe-Nph-Ala-Leu as substrate preincubated for 10 mins followed by substrate addition and measured by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4325800
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.72 | 4.12 | 4.12 |
| 523.67 | 3.91 | 3.91 |
| 494.70 | 3.09 | 3.09 |
| 515.74 | 4.42 | 4.42 |
| 529.77 | 4.81 | 4.81 |
| 503.68 | 3.34 | 3.34 |
| 558.76 | 3.29 | 3.29 |
| 471.69 | 4.67 | 4.67 |
| 459.63 | 3.00 | 3.00 |
| 473.66 | 3.25 | 3.25 |
| 535.73 | 4.22 | 4.22 |
| 503.68 | 3.86 | 3.86 |
| 443.65 | 2.32 | 2.32 |
| 501.71 | 4.03 | 4.03 |
| 593.81 | 5.22 | 5.22 |
| 505.68 | 3.78 | 3.78 |
| 521.70 | 4.35 | 4.35 |
| 493.60 | 0.18 | 0.18 |
| 536.72 | 3.62 | 3.62 |
| 501.71 | 4.03 | 4.03 |
| 527.75 | 4.56 | 4.56 |
| 502.70 | 3.43 | 3.43 |
| 425.61 | 2.80 | 2.80 |
| 556.58 | 4.94 | 4.94 |
| 453.67 | 3.44 | 3.44 |
| 537.75 | 4.79 | 4.79 |
| 487.69 | 3.64 | 3.64 |
| 489.66 | 2.36 | 2.36 |
| 533.78 | 4.33 | 4.33 |
| 493.73 | 4.36 | 4.36 |
| 579.78 | 4.59 | 4.59 |