Assay Report Card

Basic Information

ID: ALA4326404

Type: ADME

Description: Proinflammatory activity in human LAD2 cells assessed as increase in mast-cell degranulation by measuring beta-hexosaminidase release at 0.5 mM preincubated for 30 mins followed 4-nitrophenyl-N-acetyl-beta-D-glucosaminide substrate addition and measured after 90 mins by fluorescence-based microplate reader analysis relative to control

Organism: Homo sapiens

Cell type: LAD2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
971.18-5.55-5.55