Drug metabolism in human hepatocytes assessed as AO-mediated 4-(6-(2-amino-3-fluoropyridin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazo...

ID: ALA4326438

Type: ADME

Description: Drug metabolism in human hepatocytes assessed as AO-mediated 4-(6-(2-amino-3-fluoropyridin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazol-1-yl)-5,8-difluoroquinolin-2(1H)-one metabolite formation at 0.5 uM measured up to 250 mins by UHPLC-HRMS based assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Aldehyde oxidase(ALA3257)

Document:  ALA4325835

Drug metabolism in human hepatocytes assessed as AO-mediated 4-(6-(2-amino-3-fluoropyridin-4-yl)-2-methyl-4-(4H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazol-1-yl)-5,8-difluoroquinolin-2(1H)-one metabolite formation at 0.5 uM measured up to 250 mins by UHPLC-HRMS based assay: 1