ID: ALA4326666
Type: Functional
Description: Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as inhibition of LPS-induced IL-6 production at 20 uM preincubated for 60 mins followed by LPS stimulation and measured after 24 hrs by ELISA relative to control
Organism: Mus musculus
Strain: ICR
Cell type: Peritoneal macrophage
Bioactivity
Activity Types for Assay ALA4326666
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
330.46 | 2.39 | 2.39 |
420.58 | 4.00 | 4.00 |
495.61 | 4.26 | 4.26 |
476.56 | 3.74 | 3.74 |
441.51 | 3.46 | 3.46 |
496.55 | 3.77 | 3.77 |
465.58 | 4.17 | 4.17 |
424.55 | 4.10 | 4.10 |
525.48 | 4.45 | 4.45 |
456.62 | 5.11 | 5.11 |
533.70 | 5.91 | 5.91 |
456.59 | 3.15 | 3.15 |
421.57 | 3.54 | 3.54 |
424.55 | 4.10 | 4.10 |
406.56 | 3.96 | 3.96 |
431.57 | 3.83 | 3.83 |
486.62 | 3.15 | 3.15 |
475.45 | 5.26 | 5.26 |
433.49 | 1.98 | 1.98 |
451.55 | 3.86 | 3.86 |
524.59 | 4.16 | 4.16 |
466.61 | 3.97 | 3.97 |
474.55 | 4.98 | 4.98 |
431.57 | 3.83 | 3.83 |
425.51 | 3.35 | 3.35 |
511.60 | 3.88 | 3.88 |
436.58 | 3.97 | 3.97 |
451.55 | 3.86 | 3.86 |
516.65 | 3.16 | 3.16 |
420.58 | 4.26 | 4.26 |
491.04 | 3.80 | 3.80 |
530.45 | 4.63 | 4.63 |
462.66 | 5.25 | 5.25 |
441.00 | 4.61 | 4.61 |
481.58 | 3.87 | 3.87 |
421.57 | 3.54 | 3.54 |
469.54 | 4.00 | 4.00 |
530.45 | 4.63 | 4.63 |
486.00 | 4.52 | 4.52 |
487.53 | 4.14 | 4.14 |
441.00 | 4.61 | 4.61 |
436.58 | 3.97 | 3.97 |
496.55 | 3.77 | 3.77 |
497.58 | 3.58 | 3.58 |
530.45 | 4.63 | 4.63 |
491.04 | 3.80 | 3.80 |
429.55 | 3.47 | 3.47 |
501.59 | 3.05 | 3.05 |