Basic Information
ID: ALA4326667
Type: Functional
Description: Antiinflammatory activity in ICR mouse primary peritoneal macrophages assessed as inhibition of LPS-induced TNFalpha production at 20 uM preincubated for 60 mins followed by LPS stimulation and measured after 24 hrs by ELISA relative to control
Organism: Mus musculus
Strain: ICR
Cell type: Peritoneal macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4326667
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.46 | 2.39 | 2.39 |
| 420.58 | 4.00 | 4.00 |
| 495.61 | 4.26 | 4.26 |
| 476.56 | 3.74 | 3.74 |
| 441.51 | 3.46 | 3.46 |
| 496.55 | 3.77 | 3.77 |
| 465.58 | 4.17 | 4.17 |
| 424.55 | 4.10 | 4.10 |
| 525.48 | 4.45 | 4.45 |
| 456.62 | 5.11 | 5.11 |
| 533.70 | 5.91 | 5.91 |
| 456.59 | 3.15 | 3.15 |
| 421.57 | 3.54 | 3.54 |
| 424.55 | 4.10 | 4.10 |
| 406.56 | 3.96 | 3.96 |
| 431.57 | 3.83 | 3.83 |
| 486.62 | 3.15 | 3.15 |
| 475.45 | 5.26 | 5.26 |
| 433.49 | 1.98 | 1.98 |
| 451.55 | 3.86 | 3.86 |
| 524.59 | 4.16 | 4.16 |
| 466.61 | 3.97 | 3.97 |
| 474.55 | 4.98 | 4.98 |
| 431.57 | 3.83 | 3.83 |
| 425.51 | 3.35 | 3.35 |
| 511.60 | 3.88 | 3.88 |
| 436.58 | 3.97 | 3.97 |
| 451.55 | 3.86 | 3.86 |
| 516.65 | 3.16 | 3.16 |
| 420.58 | 4.26 | 4.26 |
| 491.04 | 3.80 | 3.80 |
| 530.45 | 4.63 | 4.63 |
| 462.66 | 5.25 | 5.25 |
| 441.00 | 4.61 | 4.61 |
| 481.58 | 3.87 | 3.87 |
| 421.57 | 3.54 | 3.54 |
| 469.54 | 4.00 | 4.00 |
| 530.45 | 4.63 | 4.63 |
| 486.00 | 4.52 | 4.52 |
| 487.53 | 4.14 | 4.14 |
| 441.00 | 4.61 | 4.61 |
| 436.58 | 3.97 | 3.97 |
| 496.55 | 3.77 | 3.77 |
| 497.58 | 3.58 | 3.58 |
| 530.45 | 4.63 | 4.63 |
| 491.04 | 3.80 | 3.80 |
| 429.55 | 3.47 | 3.47 |
| 501.59 | 3.05 | 3.05 |