Basic Information
ID: ALA4326773
Type: Binding
Description: Inhibition of Streptococcus pyogenes SrtA deltaN81 mutant expressed in Escherichia coli BL21(DE3) at 100 uM using Abz-LPETA-Dap(Dnp) as substrate preincubated for 10 mins followed by substrate addition measured every min for 2.5 hrs by fluorimetric assay relative to control
Organism: Streptococcus pyogenes
Activity Charts
Bioactivity
Activity Types for Assay ALA4326773
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 172.23 | 1.81 | 1.81 |
| 160.22 | 1.67 | 1.67 |
| 259.35 | 2.58 | 2.58 |
| 190.25 | 1.68 | 1.68 |
| 232.28 | 1.86 | 1.86 |
| 147.18 | 2.18 | 2.18 |
| 112.09 | -0.94 | -0.94 |
| 161.16 | 1.87 | 1.87 |
| 195.60 | 2.52 | 2.52 |
| 249.30 | 1.46 | 1.46 |
| 218.26 | 1.55 | 1.55 |
| 175.19 | 1.88 | 1.88 |
| 111.10 | -0.24 | -0.24 |
| 123.11 | 0.78 | 0.78 |
| 145.16 | 1.94 | 1.94 |
| 189.21 | 2.34 | 2.34 |
| 178.21 | 2.60 | 2.60 |
| 175.19 | 1.79 | 1.79 |
| 167.12 | 0.48 | 0.48 |
| 95.11 | 0.06 | 0.06 |
| 145.16 | 1.98 | 1.98 |
| 162.15 | 2.08 | 2.08 |
| 208.26 | 3.40 | 3.40 |
| 180.17 | -1.04 | -1.04 |
| 280.31 | 0.87 | 0.87 |
| 204.23 | 1.12 | 1.12 |
| 173.17 | 1.93 | 1.93 |
| 195.17 | 0.65 | 0.65 |
| 128.15 | 1.45 | 1.45 |
| 153.19 | 0.09 | 0.09 |
| 162.58 | 0.04 | 0.04 |
| 145.16 | 1.94 | 1.94 |
| 95.10 | 0.83 | 0.83 |
| 145.16 | 1.98 | 1.98 |
| 223.66 | 3.00 | 3.00 |
| 251.67 | 2.81 | 2.81 |
| 179.61 | 2.63 | 2.63 |
| 348.23 | 4.03 | 4.03 |
| 348.23 | 4.03 | 4.03 |
| 351.30 | 3.84 | 3.84 |
| 215.26 | 1.64 | 1.64 |
| 325.33 | 3.83 | 3.83 |
| 279.73 | 1.88 | 1.88 |
| 332.81 | 3.94 | 3.94 |
| 124.14 | 0.16 | 0.16 |
| 375.48 | 2.46 | 2.46 |
| 202.19 | 2.40 | 2.40 |
| 238.67 | 2.58 | 2.58 |
| 228.25 | 2.89 | 2.89 |
| 123.11 | -0.13 | -0.13 |
| 262.31 | 2.47 | 2.47 |
| 140.21 | 2.34 | 2.34 |
| 195.18 | -1.71 | -1.71 |
| 200.24 | 1.46 | 1.46 |
| 184.22 | 1.80 | 1.80 |
| 310.81 | 1.50 | 1.50 |
| 175.19 | 1.95 | 1.95 |
| 323.78 | 4.40 | 4.40 |
| 296.37 | 2.76 | 2.76 |
| 292.33 | 4.39 | 4.39 |
| 227.26 | 2.73 | 2.73 |
| 209.63 | 2.61 | 2.61 |
| 286.34 | 0.99 | 0.99 |
| 295.68 | 2.57 | 2.57 |
| 272.35 | 2.71 | 2.71 |
| 294.33 | 2.37 | 2.37 |
| 180.59 | 2.03 | 2.03 |
| 287.77 | 4.53 | 4.53 |
| 322.37 | 1.92 | 1.92 |
| 326.78 | 4.75 | 4.75 |
| 366.42 | 2.44 | 2.44 |
| 271.32 | 3.08 | 3.08 |
| 220.28 | 0.54 | 0.54 |
| 348.19 | 4.60 | 4.60 |
| 179.61 | 2.63 | 2.63 |
| 267.67 | 2.70 | 2.70 |
| 337.76 | 3.13 | 3.13 |
| 314.78 | 2.72 | 2.72 |