Basic Information
ID: ALA4326815
Type: Binding
Description: Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring cell survival at 5 uM after 72 hrs by MTT assay (Rvb = 104 +/- 8%)
Format: BAO_0000219
Organism: Homo sapiens
Target: P-glycoprotein 1(ALA4302)
Document: ALA4325852
Reversal of P-gp-mediated multidrug resistance in human KBV cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring cell survival at 5 uM after 72 hrs by MTT assay (Rvb = 104 +/- 8%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4326815
Survival
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 476.74 | 5.71 | 5.71 |
| 476.74 | 5.71 | 5.71 |
| 594.88 | 6.73 | 6.73 |
| 573.90 | 7.42 | 7.42 |
| 595.87 | 6.86 | 6.86 |
| 717.09 | 8.70 | 8.70 |
| 632.93 | 6.36 | 6.36 |
| 560.86 | 5.57 | 5.57 |
| 717.09 | 8.70 | 8.70 |
| 532.81 | 4.79 | 4.79 |
| 616.97 | 7.14 | 7.14 |
| 580.85 | 6.54 | 6.54 |
| 532.81 | 4.79 | 4.79 |
| 580.85 | 6.54 | 6.54 |
| 601.96 | 8.20 | 8.20 |
| 623.88 | 6.85 | 6.85 |
| 573.90 | 7.42 | 7.42 |
| 588.92 | 6.35 | 6.35 |
| 588.92 | 6.35 | 6.35 |
| 475.76 | 5.68 | 5.68 |
| 475.76 | 5.68 | 5.68 |
| 560.86 | 5.57 | 5.57 |
| 579.87 | 7.15 | 7.15 |
| 579.87 | 7.15 | 7.15 |
| 595.87 | 6.86 | 6.86 |
| 695.00 | 8.50 | 8.50 |
| 616.97 | 7.14 | 7.14 |
| 632.93 | 6.36 | 6.36 |
| 689.03 | 7.92 | 7.92 |
| 545.85 | 6.64 | 6.64 |
| 689.03 | 7.92 | 7.92 |
| 660.98 | 7.14 | 7.14 |
| 660.98 | 7.14 | 7.14 |