Basic Information
ID: ALA4326999
Type: Binding
Description: Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation and measured after 24 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MONO-MAC-6
Target: c-Jun N-terminal kinase, JNK(ALA2096667)
Document: ALA4325855
Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production preincubated for 30 mins followed by LPS-stimulation and measured after 24 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4326999
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 220.23 | 2.77 | 2.77 |
| 263.26 | 1.93 | 1.93 |
| 247.26 | 2.84 | 2.84 |
| 261.28 | 3.15 | 3.15 |
| 275.31 | 3.45 | 3.45 |
| 282.69 | 2.89 | 2.89 |
| 292.25 | 2.75 | 2.75 |
| 248.25 | 2.23 | 2.23 |
| 261.28 | 3.15 | 3.15 |
| 291.31 | 3.24 | 3.24 |
| 291.31 | 2.37 | 2.37 |
| 291.27 | 2.54 | 2.54 |
| 333.35 | 2.94 | 2.94 |
| 281.70 | 3.49 | 3.49 |
| 248.25 | 2.23 | 2.23 |