Basic Information
ID: ALA4327000
Type: Binding
Description: Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production at <40 uM preincubated for 30 mins followed by LPS-stimulation and measured after 24 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MONO-MAC-6
Target: c-Jun N-terminal kinase, JNK(ALA2096667)
Document: ALA4325855
Inhibition of JNK in human MONO-MAC-6 cells assessed as reduction in LPS-induced IL6 production at <40 uM preincubated for 30 mins followed by LPS-stimulation and measured after 24 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4327000
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.24 | 1.93 | 1.93 |
| 287.32 | 3.57 | 3.57 |
| 337.38 | 4.58 | 4.58 |
| 338.13 | 4.14 | 4.14 |
| 275.31 | 3.40 | 3.40 |
| 261.28 | 3.01 | 3.01 |
| 305.29 | 2.46 | 2.46 |
| 337.24 | 3.86 | 3.86 |
| 303.37 | 4.04 | 4.04 |